Description
What this medicine is for
Malarone Tablets contain atovaquone 250mg and proguanil hydrochloride 100mg. They are used for the prevention and treatment of malaria, particularly infections caused by Plasmodium falciparum, the most severe form of malaria.
Malarone is commonly recommended for travellers visiting high-risk malaria regions, including parts of Africa, South America, and Asia. It is also used under medical supervision to treat active malaria infections.
How it works
Malarone works through a dual-action mechanism:
Atovaquone disrupts the parasite’s energy production, while proguanil enhances this effect and interferes with the parasite’s ability to replicate.
Together, they stop the malaria parasite from growing and spreading in the bloodstream.
Key Benefits
- Dual-action antimalarial protection
- Effective against chloroquine-resistant P. falciparum
- Once-daily dosing for convenience
- Short pre- and post-travel treatment course
- Suitable for adults and children (child doses available)
Directions for Use
Prevention
- Start 1–2 days before travel
- Take 1 tablet daily during exposure in malaria-risk areas
- Continue for 7 days after leaving the risk area
Treatment
- Use only as prescribed by a healthcare professional
- Follow the exact dosage and duration given by your doctor
Warnings
Prescription-only medicine. Not suitable for everyone—medical travel consultation is required before use.
Use with caution in individuals with kidney or liver conditions.
Always complete the full prescribed course.
Seek medical advice if symptoms of malaria occur despite prophylaxis.
Possible Side Effects
- Headache
- Nausea
- Abdominal pain
- Diarrhoea
- Dizziness
- Mild skin rash
Patient Information Leaflet (PIL)
Please refer to the official patient information leaflet for full safety information, dosing guidance, and instructions before use.
https://www.medicines.org.uk/emc/files/pil.947.pdf
Important information
Tell your healthcare provider if you:
- Have kidney or liver disease
- Are taking other medications
- Are pregnant, planning pregnancy, or breastfeeding
- Develop symptoms of malaria during or after travel
Please note: The product you receive may differ from the images shown above in terms of packaging.
Written and Reviewed by Medical Professionals


Reviews
There are no reviews yet.